The invention relates to biomimetic peptide-containing compositions for use, in particular, for appliion and or deposition on a magnesium alloy, e.g., substrate, to at least partially coat a surface of the magnesium alloy. The invention also relates to the coated magnesium alloy which is particularly useful for tissue and bone repair and regeneration appliions, such as, for constructing
19.09.2013· Magnesium alloy AZ91D is used, for example, by Phillips Magnesium Injection Molding, Eau Claire, Wisconsin, to form 15 different parts (power input mount housing; manifold cover; docking station battery door; RAM access, CMOS, PCMCIA, DVD, computer battery and hard drive doors; bezel for display screen frame and cover for back of display screen; the computer chassis and cover; and …
Implant-associated infection is one of the biggest problems in orthopedic surgery. Antimicrobial peptides (AMPs) are well-known components of the innate immunity and less susceptible to the development of pathogen resistance compared to conventional antibiotics. Magnesium alloys as potential biodegr …
FIELD: medicine. SUBSTANCE: group of inventions refers to medicine, particularly to production of medical implant from magnesium alloy, in which content of magnesium is, at least, 80 wt%, in particular, at least, 90 wt%, which includes the following steps: a) melting of magnesium alloy to produce molten alloy; b) atomization of molten alloy in atmosphere of protective gas and cooling of …
These non-implant products include external fixation devices and braces, as well as specialty products for recreational sports equipment and manufacturing uses. Put simply, at nanoMAG we work in close collaboration with our clients to create, develop and manufacture specialty magnesium alloy products.
An implant made in total or in parts of a biodegradable magnesium alloy consisting of Y: 2.0-6.0% by weight, Nd: 1.5-4.5% by weight, Gd: 0-4.0% by weight, Dy: 0-4.0% by weight, Er: 0-4.0% by weight, Zr: 0.1-1.0% by weight, Li: 0-0.2% by weight, Al: 0-0.3% by weight, under the condition that a) a total content of Er, Gd and Dy is in the range of 0.5-4.0% by weight and b) a total content of Nd
The effect of ions in the surrounding solutions on the surface degradation of magnesium alloys, a well-recognized biodegradable biomaterial, has been neglected compared with the effect of anions in the past. To better simulate the compressive environment where magnesium alloys are implanted into the body as a cardiovascular stent, a device is designed and employed in the test so that a
Properties, sources and uses of the element magnesium. Some compounds include magnesium citrate, magnesium oxide and magnesium chloride.
Magnesium Alloys (magnesium-based alloys), the strongest and most refractory alloys. They are prepared from a base of magnesium and a metal with limited solubility in solid magnesium. Because of the high chemical activity of magnesium, the nuer of metals suitable for the production of magnesium alloys is relatively small. Magnesium alloys are divided
In order to investigate the in vivo behavior of pure magnesium and AZ31B and the influence of mineralization induction ability, sample rods were implanted intramedullary into the femora of rabbits. After one and nine weeks, six animals from each group were saced, respectively. Undecalcified cross-sections of implant were performed to observe bone-implant by scanning electron microscopy
Researchers also recently created a new low-cost alloy based on aluminum, calcium and magnesium, which may prove useful for lightweight, high-temperature components in automotive powertrains.
In addition, the elastic modulus of magnesium is well-matched with that of natural bone, resulting in the reduction of stress shielding effect that can lead to bone loss around the implant. Unlike traditional permanent implants, such as Ti alloys and stainless steels, biodegradable magnesium alloys will not cause permanent physical irritation or chronic inflammatory discomfort.
A method for manufacturing a bioresorbable implant, wherein a magnesium alloy is formed into an implant. A melt is pressed into a die and gases in the die induce turbulence in the inflowing melt, thereby enclosing gas, so that the porous implant is formed with a porosity, which increases from outside inwardly. The surface of the implant is substantially free from open pores.
Investigation on the Potential of Magnesium Alloy AZ31 as a Bone Implant Degradable implants have been in use for bone surgery for decades. However, degradable metal implants are one of the new research areas of biomaterials science. There is a potential for appliion of degradable metal implants as screws and plates in bones.
Degradable implants have been in use for bone surgery for decades. However, degradable metal implants are one of the new research areas of biomaterials science. There is a potential for appliion of degradable metal implants as screws and plates in bones.
Bioresorbable (also called biodegradable or bioabsorbable) metals are metals or their alloys that degrade safely within the body. The primary metals in this egory are magnesium-based and iron-based alloys, although recently zinc has also been investigated. Currently, the primary uses of bioresorbable metals are as stents for blood vessels (for example bioresorbable stents) and other
M. Bornapour, M. Celikin, M. Cerruti, and M. Pekguleryuz, “Magnesium implant alloy with low levels of strontium and calcium: The third element effect and phase selection improve bio-corrosion resistance and mechanical performance,” Materials Science and Engineering C: Materials for Biological Appliions, vol. 35, no. 1, pp. 267–282, 2014.
Through the analysis of the above, it suggested that Mg–1Ca alloy has good biocompatibility as a potential biodegradable implant material. Gu et al. [ 52 , 114 ] developed the binary alloys Mg–1X (wt.%) with nine kinds of elements, namely, including Al, Ag, In, Mn, Si, Sn, Y, Zn and Zr and Mg–XSr (1–4 wt.%) to study the corrosion resistance of Mg alloys, and they observed the
Biodegradation of a magnesium alloy implant in the intercondylar femoral notch showed an appropriate response to the synovial merane in a rabbit model in vivo Marco Ezechieli1, Julia Diekmann1,2, Andreas Weizbauer1,2, Christoph Becher1, Elmar Willbold1, Patrick Helmecke3, Arne Lucas4, Robert Schavan4 and Henning Windhagen1 Abstract
The invention relates to an implant made in total or in parts of a biodegradable magnesium alloy consisting of Y: 2.0 - 6.0% by weight, Nd: 1.5 - 4.5% by weight, Gd: 0 - 4.0% by weight, Dy: 0 - 4.0% by weight, Er: 0 - 4.0% by weight, Zr: 0.1 - 1.0% by weight, Li:0 - 0.2% by weight, Al: 0 - 0.3% by weight, under the condition that a) a total content of Er, Gd and Dy is in the range of 0.5 - 4.0
24.08.2020· Aluminium does not react with water. Its surface is protected by a natural layer of aluminium oxide that allows the metal to resist corrosion. Aluminium foil is used for wrapping and storing food
Biomedical implant can be divided into permanent and temporary employment. The duration of a temporary implant applied to children and adult is different due to different bone healing rate among the children and adult. Magnesium and its alloys are compatible for the biodegradable implanting appliion.
This system was developed to use the magnesium alloy AZ61 (Mg-6Al-1Zn). Although the theoretical open circuit EMF for this type of cell is 2.6 V practical working voltages are of the order of 1.1 V. Uses in hodic projection. Cast magnesium anodes are usually supplied in AZ63 (Mg-6Al-3Zn) and extruded shapes in AZ61 (Mg-6Al-1Zn) alloys.
Magnesium alloys have similar mechanical properties with natural bone, and they degrade within a certain time span. Therefore, magnesium alloys are suitable to be made as bone screws or plates. However, high susceptibility to corrosion has limited their appliions in the orthopedic field. They would possess great medical functions if the degradation rates of magnesium alloys could be reduced.
Magnesium (Mg) and its alloys can degrade gradually up to complete dissolution in the physiological environment. This property makes these biomaterials appealing for different biomedical appliions, such as bone implants. In order to qualify Mg and its alloys for bone implant appliions, there i …
In such uses the implant material must possesses an adequate resistance to cracking such as corrosion-assisted-cracking fractures including stress corrosion cracking (SCC) and corrosion fatigue (CF). This study evaluates SCC of an extruded Mg alloy, ZK21, using slow strain rate tensile (SSRT) testing at a strain rate of 3.1 × 10−7 in modified simulated body fluid (m-SBF) at 37 °C.
Biodegradation of a magnesium alloy implant in the intercondylar femoral notch showed an appropriate response to the synovial merane in a rabbit model in vivo Marco Ezechieli, Julia Diekmann, Andreas Weizbauer, Christoph Becher, Elmar Willbold, Patrick Helmecke, Arne Lucas, Robert Schavan, and Henning Windhagen